Publications

V Swaminathan* and M Gloerich*. (2021) Decoding mechanical cues by molecular mechanotransduction. Current Opinion in Cell Biology, Jul 1;72:72-80. doi: 10.1016/j.ceb.2021.05.006

Shan Wang Emelie EnglundPontus KjellmanZhen LiJohannes Kumra AhnlideCarmen Rodriguez-CupelloMattia SaggioroRyu KanzakiKristian PietrasDavid LindgrenHåkan AxelsonChristelle N PrinzV SwaminathanChris D Madsen. (2021) CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling. Nature Cell Biology, doi: 10.1038/s41556-021-00702-0. *Note: Recently, a number of potential problems with this paper have been discussed at Pubpeer (https://pubpeer.com/publications/AAB9690BBF9C198C23AE3D6A72846F). This has led to an investigation within the corresponding authors laboratory and institute. Until further notice, this should be considered by all readers of this work and visitors to this website. .

W Sturgess and V Swaminathan. (2021) Focal adhesion isolation assay using ECM-coated magnetic beads. Methods in Molecular Biology, The Integrin Interactome, pp39-44

V Swaminathan, G Alushin, CM Waterman. (2017) Mechanosensation: A catch bond that hooks only way. Current Biology 27, R1158-1160

P Nordenfelt, T Moore, S Mehta, JK Mathew, V Swaminathan, K Nobuyasu, D Baker, T Tani, S Mayor, CM Waterman, TA Springer. (2017) Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration. Nature Communication 8, Article Number 2047.

V Swaminathan*, Joseph K Mathew*, S Mehta*, P Nordenfelt, T Moore, K Nobuyasu, D Baker, T Tani, S Mayor, TA Springer, CM Waterman. (2017) Actin retrograde flow orients and aligns activated, ligand- engaged integrins in focal adhesions. Proc. Natl. Acad. Sci. pp 10648-10653

V Swaminathan, CM Waterman. (2016) Modern microscopy approaches to study integrin-based adhesions. Molecular and Cellular Mechanobiology pp 119-140

V Swaminathan, CM Waterman. (2016) The molecular clutch model for mechanotransduction evolves. Nature Cell Biology 18, 459-461.

V Swaminathan, RS Fischer, C Waterman. (2016) The FAK-Arp2/3 interaction promotes leading edge advance and haptosensing by coupling nascent adhesions to lamellipodial actin. Mol. Biol. Cell. 27 (1085- 1100)

K Shen, CE Tolbert, C Guilluy, VS Swaminathan, ME Berginski, K Burridge, R Superfine, SL Campbell. (2011) The Vinculin C-terminal hairpin mediates F-actin bundle formation, focal adhesion, and cell mechanical properties. Journal of Biological Chemistry 286 (52). 45103-45115.

V Swaminathan*, K Mythreye*, ET O’Brien, A Berchuck, GC Blobe, R Superfine. (2011) Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines. Cancer research 71 (15) 5075-5080.

C Guilluy*, V Swaminathan*, R Garcia-Mata, ET O’Brien, R Superfine, K Burridge.(2011) The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on Integrins. Nature Cell Biology 13, 722- 727.

DB Hill, V Swaminathan, A Estes, J Cribb, ET O’Brien, CW Davis, R Superfine. Force generation and dynamics of individual cilia under external loading. Biophysical Journal. 98 (1). 57-66.

MK Ramasubramanian, OM Barnham, V Swaminathan. (2008) Mechanics of a mosquito bite with applications to microneedle design. Bioinspiration & Biomimetics 3(4) 046001

RC Spero, L Vicci, J Cribb, D Bober, V Swaminathan, ET O’Brien, SL Rogers, R Superfine. (2008) High Throughput system for magnetic manipulations of cells, polymers and biomaterials. Review of Scientific Instruments 79(8).